IMBB SEMINAR
Michalis KOTSYFAKIS
Head of the Laboratory of Genomics and Proteomics of Disease Vectors,
Biology Center of the Czech Academy of Sciences,
Budweis, Czech Republic
Title: "The tick Ixodes ricinus as a model organism for discovering potent pharmacological activities"
Friday, December 1st, 2017 @ 12:00
“Seminar Room 1”, FORTH’s bldg
Host: I. Siden -Kiamos
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1. Hackenberg M, Langenberger D, Schwarz A, Erhart J, Kotsyfakis M. In silico target network analysis of de novo-discovered, tick saliva-specific microRNAs reveals important combinatorial effects in their interference with vertebrate host physiology.
RNA. 2017 Aug;23(8):1259-1269.
2. Chmelař J, Kotál J, Karim S, Kopacek P, Francischetti IM, Pedra JH, Kotsyfakis M. Sialomes and Mialomes: A systems-biology view of tick tissues and tick-host interactions.
Trends Parasitol. 2016 Mar;32(3):242-54.
3. Schwarz A, Tenzer S, Hackenberg M, Erhart J, Gerhold-Ay A, Mazur J, Kuharev J, Ribeiro JM, Kotsyfakis M. A systems level analysis reveals transcriptomic and proteomic complexity in Ixodes ricinus midgut and salivary glands during early attachment and feeding.
Mol Cell Proteomics. 2014 Oct;13(10):2725-35.
4. Schwarz A, von Reumont BM, Erhart J, Chagas AC, Ribeiro JM, Kotsyfakis M. De novo Ixodes ricinus salivary gland transcriptome analysis using two next-generation sequencing methodologies.
FASEB J. 2013 Dec;27(12):4745-56.
5. Chmelar J, Oliveira CJ, Rezacova P, Francischetti IM, Kovarova Z, Pejler G, Kopacek P, Ribeiro JM, Mares M, Kopecky J, Kotsyfakis M. A tick salivary protein targets cathepsin G and chymase and inhibits host inflammation and platelet aggregation.
Blood. 2011 Jan 13;117(2):736-44.
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http://www.youtube.com/channel/UCPeRZVC0qvjFt83jDtYTyqA